Some loss of memory is to be expected as you age. Much of it is caused by the normal wear-and-tear on the brain. But some of it may be caused by your medicine. Several classes of medications are already known to impair memory. New research confirms one of the suspects. Anticholinergic medications –commonly prescribed drugs used to treat ulcers, stomach cramps, motion sickness, Parkinson's disease, and urinary incontinence—may cause older people to lose their cognitive skills more quickly than seniors who don't take the medicines.
Anticholinergic drugs block a brain chemical called acetylcholine, an important player in memory and cognitive performance. Researchers, who presented their findings at the 2008 American Academy of Neurology annual meeting, studied 870 Catholic nuns and clergy members who are part of an ongoing study of older people called the Rush Religious Orders Study. During eight years of follow-up, those who took anticholinergic drugs saw their cognitive function decline 1.5 times faster than those not on the drugs. The researchers found that the medications used for bladder problems and Parkinson’s seemed to have the worst effect on memory.
If you’re on anticholinergic medicines, be sure to discuss these findings with your doctors, especially if you suspect any changes in your memory.
SOURCES: American Academy of Neurology; National Library of Medicine
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